Online Guest Lecture: Plasma Exchange Therapy and Role of Brain Vasculature in Alzheimer’s Disease under the International Learning Exchange Series (Session III)

Published on: April 21, 2026

The School of Biosciences at Swami Rama Himalayan University (SRHU) successfully organized the third session of its International Learning Exchange Series, a dedicated initiative designed to bridge the gap between regional academic learning and global scientific frontiers. The online guest lecture featured Dr. Santiago Ramirez, a Senior Research Scientist at the Mitchell Center for Alzheimer’s Disease and Related Brain Disorders, UTHealth Houston, USA, who presented on the theme “Plasma Exchange Therapy and Role of Brain vasculature in Alzheimer’s Disease.”

The lecture provided a profound exploration of the neurovascular unit and its critical role in the pathogenesis of Alzheimer’s disease. Dr. Ramirez detailed his cutting-edge research on how targeting the “periphery” specifically through plasma exchange, can mitigate the accumulation of toxic amyloid-beta proteins in the brain. He shared compelling evidence on how these innovative therapeutic interventions can potentially restore vascular integrity and slow cognitive decline, offering a fresh perspective that moves beyond traditional intra-cerebral treatments.

During the session, Dr. Ramirez, drawing from his unique background as a DVM and surgeon, discussed the complexities of translational medicine. He highlighted the importance of using advanced models and innovative approaches to better understand human disease. He encouraged students to adopt a multidisciplinary approach to scientific inquiry, emphasizing that the most impactful solutions often lie at the intersection of different biological disciplines.

The event concluded with an extensive Q&A session, where Dr. Ramirez addressed high-level technical queries regarding blood-brain barrier permeability, the “peripheral sink” hypothesis, and the challenges of translating animal model successes into human clinical practice. As the third instalment of the International Learning Exchange Series, this session reinforced the University’s commitment to academic excellence by providing scholars with direct interaction with world-class researchers at the forefront of neurodegeneration studies.

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International Endowed Chair Professor

Prof Rakesh Kumar

Prof Rakesh Kumar is the Founder and President of the Breast Cancer in Young Women Foundation (USA), dedicated to vaddressing the distinct issues affecting young women with breast cancer. He also serves as the International Endowed Chair Professor at the Cancer Research Institute of the Himalayan Institute of Medical Sciences. Additionally, he holds adjunct professorships at Rutgers New Jersey Medical School and Virginia Commonwealth University.

Dr Kumar earned his Ph.D. from the All India Institute of Medical Sciences in 1984 and began his research career at Memorial Sloan Kettering Cancer Center in January 1986. From 1988 to 2017, he held various academic and leadership positions —including faculty member, tenured professor, distinguished professor, endowed chair, department chair, and research leader—at esteemed institutions such as Memorial Sloan Kettering Cancer Center in New York and the University of Texas MD Anderson Cancer Center in Houston. From 2017 to 2022, he served as the National Chair for Cancer Research for the Government of India and as a distinguished professor, continuing his innovative work in breast cancer research.

With nearly 40 years of research and professional experience, Dr. Kumar has made conceptual contributions to the field of cancer research (h-index 108, citations >50,000). He has authored over 325 peer-reviewed publications, edited or co-edited nine books, and delivered 290 invited lectures worldwide. His work has been featured on the covers of 18 major cancer journals and has been highlighted in institutional research reports of the MD Anderson Cancer Center.

A passionate educator and mentor, Dr. Kumar has guided 67 trainees throughout his career. He serves on the editorial boards of multiple leading cancer journals and has served on the editorial boards of 21 top cancer journals. His global reputation is further demonstrated by his participation in about 100 peer-review panels for cancer research funding in the US and internationally over the past 28 years.

Dr. Kumar's innovative research has earned him numerous prestigious honors, including the Hinkle Society Faculty Award at Penn State University (1994), the Dalla/Fort Worth Living Legend Faculty Achievement Award in Basic Sciences (2004), the Ranbaxy Research Award (2006), and the Lifetime Achievement Award from the American Association of Indian Scientists in Cancer Research (2013), among others. Dr. Kumar's pioneering research continues to have a profound influence on the fields of oncology and breast cancer, opening up new opportunities for biomedical scientists and trainees worldwide.